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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF4B
All Species:
30.3
Human Site:
S431
Identified Species:
55.56
UniProt:
Q13523
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13523
NP_003904.3
1007
116973
S431
R
E
R
S
K
D
A
S
P
I
N
R
W
S
P
Chimpanzee
Pan troglodytes
XP_518214
1087
126250
S511
R
E
R
S
K
D
A
S
P
I
N
R
W
S
P
Rhesus Macaque
Macaca mulatta
XP_001094163
1007
116833
S431
R
E
R
S
K
D
A
S
P
I
N
R
W
S
P
Dog
Lupus familis
XP_848551
1042
120804
S465
R
E
R
S
K
D
A
S
P
L
N
R
W
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61136
1007
116929
S431
C
E
R
S
K
D
A
S
P
I
N
R
W
S
P
Rat
Rattus norvegicus
Q5RKH1
1007
116988
S431
C
E
R
S
K
D
A
S
P
I
N
R
W
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508424
1011
117270
S434
R
E
R
S
K
D
V
S
P
I
S
R
W
S
P
Chicken
Gallus gallus
XP_001232309
1005
116507
P430
E
R
S
K
D
I
S
P
P
S
R
W
S
P
S
Frog
Xenopus laevis
NP_001088314
991
115012
S416
H
D
R
A
K
E
A
S
P
S
R
W
S
P
S
Zebra Danio
Brachydanio rerio
NP_998614
1010
116034
P447
R
R
R
V
S
R
S
P
L
R
R
R
S
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_612010
907
104024
S414
D
R
D
R
Y
K
G
S
L
S
E
G
Q
N
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492008
775
90931
N324
P
V
S
I
Q
S
D
N
D
T
P
T
D
F
F
Sea Urchin
Strong. purpuratus
XP_791787
924
105587
S401
P
L
E
R
R
I
R
S
S
R
S
P
A
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
99
95.3
N.A.
95.1
95.4
N.A.
93
89.7
80.6
68.8
N.A.
41.4
N.A.
36.8
48.3
Protein Similarity:
100
92.6
99.3
96.1
N.A.
97.5
97.8
N.A.
96.5
94
89.4
78.4
N.A.
57.4
N.A.
51.9
59.9
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
6.6
33.3
20
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
13.3
53.3
26.6
N.A.
13.3
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
54
0
0
0
0
0
8
0
0
% A
% Cys:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
8
54
8
0
8
0
0
0
8
0
0
% D
% Glu:
8
54
8
0
0
8
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
16
0
0
0
47
0
0
0
0
0
% I
% Lys:
0
0
0
8
62
8
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
8
0
0
0
0
0
0
16
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
47
0
0
8
0
% N
% Pro:
16
0
0
0
0
0
0
16
70
0
8
8
0
16
54
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
47
24
70
16
8
8
8
0
0
16
24
62
0
0
0
% R
% Ser:
0
0
16
54
8
8
16
77
8
24
16
0
24
54
24
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% T
% Val:
0
8
0
8
0
0
8
0
0
0
0
0
0
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
16
54
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _